透明质酸钠不与蛋白质共价结合,但广泛分布于结缔组织中。在化学中,透明质酸是一种具有-COOH和-OH官能团的亲水性大分子。其在水中的溶解度高,可形成高粘度溶液,由此显示出它的独特粘弹性。透明质酸钠可以形成分子内氢键,从而形成三维结构,所以在其结构内捕获水分并形成凝胶。透明质酸钠也可以参与反应或交联,但部分大分子或中分子物质难以穿透皮肤渗透至其作用区域,或对其释放速率和时间有一定的要求,从而调整其化学性质和耐水溶解性。捕获的水量约为其重量的1000倍。透明质酸钠的溶液和凝胶通常用作皮肤填充剂。注射后,可以恢复皮肤体积并尽量减少皱纹的出现,也是化妆品配方,医疗和美容原料中非常有效和安全的成分。
文献:
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